The last time four consecutive home runs were hit in the National League was Sept. 18, 2006, when the Dodgers did it in the bottom of the ninth.
"It's not very often that happens," D-backs manager Kirk Gibson said. "I was happy to be a part of it for sure. The guys really hit the ball that inning."
First baseman Adam LaRoche got things started, belting a full-count fastball from Brewers starter Dave Bush deep to right field. Miguel Montero followed with the second, sending a low 1-2 fastball into the seats to tie the game at 2.
At that point, the D-backs had matched the Brewers' back-to-back home runs of two innings earlier, but they were far from finished.
Mark Reynolds snapped a personal streak of four consecutive strikeouts against Bush, belting a 1-1 curveball to left-center. The last time the D-backs had gone back-to-back-to-back was May 3, 2002, against the Montreal Expos.
"I just wanted to get a hit," Reynolds said. "I didn't [care] if it was a homer or a swinging bunt. I've been struggling since I got hit in the head. It was a curveball kind of middle away, and I didn't even swing very hard at it. I just put the barrel on it."
Finally, shortstop Stephen Drew ripped a 1-0 fastball into the D-backs bullpen in right, tying the Major League record for consecutive home runs.
Drew joins his brother, J.D., as the only brothers to have participated in a string of four straight home runs.
"It was pretty wild," Drew said. "[LaRoche] starts it off, then you see Miggy hit one and I was like 'What next?' Then Mark gets up there and hits one and I'm like, 'What am I supposed to do here?'
"It's pretty special. You don't see that too often, and it's one of those things that was meant to be, and it was a special time."
Bush is the first pitcher to give up four straight home runs since Chase Wright -- who is now in the Brewers' system -- surrendered four to the Red Sox while with the Yankees in 2007.
J.D. Drew was involved in the Dodgers-Padres feat and in the Red Sox-Yankees game.
"I remember watching it on TV that night when J.D. was with L.A., but I don't remember the one in Boston," Drew said. "He's one up on me."