Willie Bloomquist got the start in his place at shortstop, and D-backs manager Kirk Gibson said he was not sure if Drew would be available to pinch-hit if needed.
"It's pretty frustrating," Drew said of missing the opener. "But I look at it like we have 162 games, so Opening Day is great, but at the same time, it's a long season. It's not just a sprint, it's a marathon. If I can get back to where I need to be the next two or three days and can play the rest of the season, that's a big key."
Bloomquist did not play a lot of shortstop during the spring and saw action in just one game there last year. However, he has played 150 games there over his eight-year career, including 38 in 2009 for the Royals.
"We'll find out," Bloomquist said when asked if he was comfortable at the position. "It's one of those things where when you bounce around as much as I do, you really never get completely comfortable in one spot before you're off to the next spot. So it's just one of those things where you learn to deal with it and be comfortable being uncomfortable. I'm just going to go out and play as best I can."
Gibson said he had no reservations about Bloomquist's ability.
"He's gotten enough action out there," Gibson said. "He's played enough over there, he's a gamer. I'm very comfortable with him over there."