After playing in three straight games for the second time during his Minor League rehab stint, Drew was transferred from Triple-A Reno to Double-A Mobile on Friday.
Drew is scheduled to play for the BayBears on Sunday and Monday, and if all goes well, he will rejoin his teammates Wednesday in time for the second game of a three-game set with the Braves.
D-backs manager Kirk Gibson said he was not sure exactly how many days in a row Drew would initially be able to play.
"I don't have an answer for you at this time," Gibson said. "I don't know that I can sit there and say that he'll be available one day, two days, three days in a row. He may play a day and get really sore the next day, so I can't give you a concrete answer. We'll get him involved when we think he can help the team win, at the same time make sure we keep his ankle in [good] condition, give good consideration to that."
Drew suffered a season-ending ankle fracture last July 20 sliding into home. Willie Bloomquist and John McDonald have done a nice job at short in his absence, and Gibson has had the pair taking grounders at third base over the last week.
When Drew returns, it's possible that one way to get Bloomquist or McDonald in the lineup would be to play them at third.
"It's possible," Gibson said. "Obviously, the rotation will be a little different. I don't think we've figured out exactly how that rotation will be. We have a lot of flexibility there."