The D-backs, short on outfielders with Conor Jackson going on the disabled list, called up outfielder Gerardo Parra from Double-A Mobile on Wednesday and put him into the starting lineup.
The 21-year-old from Venezuela had a good Spring Training with the D-backs and performed well in the World Baseball Classic. Parra can play all three outfield positions.
"I think we're willing to change things and see if we can find the right ingredients," D-backs manager A.J. Hinch said before Wednesday's game. "He plays with a good spirit, he plays with passion. We need more of that, and it will be exciting to see him out there on the field."
Parra hit .361 with three homers and 12 RBIs in 29 games for Mobile.
He wasn't the only player making his Major League debut for the D-backs on Wednesday. Right-hander Bryan Augenstein, 22, got his first big league start against the Reds.
To make room on the roster for the two rookies, Arizona designated shortstop Josh Wilson for assignment and optioned reliever Clay Zavada to Mobile. Jackson was placed on the DL with an unidentified illness.
John Schlegel is a national reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.