David Peralta raced towards the wall and a fan reached over the wall and caught the ball.
After discussing the play with first-base umpire Chris Guccione, D-backs manager Kirk Gibson challenged the call, claiming that Frazier should be ruled out on fan interference.
Following a review, the play stood as called, meaning that there was not clear and convincing evidence to overturn the call.
Frazier went on to strike out later in the at-bat.
Steve Gilbert is a reporter for MLB.com. Read his blog, Inside the D-backs, and follow him on Twitter @SteveGilbertMLB. This story was not subject to the approval of Major League Baseball or its clubs.